Craniofacial Distraction Osteogenesis by Alexander M. Cherkashin, technique mastered by the lead author, Mikhail L. Samchukov, MD. Read Craniofacial Distraction Osteogenesis book reviews & author details and Mikhail L. Samchukov, MD, Associate Director of Ilizarov Research, Texas. Jason B. Cope, Mikhail L. Samchukov, Alexander M. Cherkashin Mechanisms of New Bone Formation During Distraction Osteogenesis: A Preliminary Report.

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Focal areas of cartilage atrophy and necrosis may occur and lead to dystrophic changes and permanent damage to joint function. Fluid flow shear stress stimulates human osteoblast proliferation and differentiation through multiple interacting and competing signal transduction pathways. Long-term effect of mandibular midline distraction osteogenesis on the status of the temporomandibular joint, teeth, periodontal structures, and neurosensory function. The radiograph shows hypotrophic regenerate with very little mineralisation indicated by arrow.

Molecular events and mechanism of bone formation in distraction osteogenesis in humans. This type of spindle-shaped cell is situated peripherally and throughout the vessels, producing more type I collagen parallel to the distraction vector. Deformity correction, lengthening, widening, bone transport, and alveolar ridge augmentation of the mandible, midface and upper face, in both congenital and acquired conditions.

We use cookies to give you the best possible experience. It is most commonly used for the correction samdhukov more severe deformities and syndromes of both the maxilla and the mandible and can also be used in children at osteogenesks previously untreatable.

Maxillary and Midface Distraction In Rachmiel and co-authors first demonstrated the possibility of maxillary distraction in their study; they performed midface gradual advancement on five sheep. Simultaneous midface and forehead distraction using internal devices after Le Fort IV osteotomy has also been reported.

Gi-proteins were confirmed to co-localize with stretch-activated calcium channel. The anchoring pins of the distraction osteogsnesis may also cause focal gradual compression. The tension-stress effect on the genesis and growth of tissues. This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.

Distraction osteogenesis of the human craniofacial skeleton: For distractors with simulated soft tissues, the closer to the inferior border, the less the deflection from the x-axis.


Another interesting modification of the bone transport technique has been experimentally and clinically applied by Liou and Huang. Segmental mandible craniotacial by distraction osteogenesis.

Experience with distraction osteogenesis model. Too much rigidity of the plate leads to stress shielding effect causing mechanical stress bypass, which apparently prevents the final stages of normal bone reconstitution.

Razdolsky developed a series of tooth-borne and hybrid ROD devices[ 1213 ] In addition he designed a special laboratory instrument to allow preprogrammed fabrication of the device along the predetermined axis of distraction based on preoperative records.

The major advantages of the intraoral devices were the inconspicuous nature of the devices and absence of facial scars.

All the distractors are made up of L stainless steel of density 4. Mechanotransduction Mechanotransduction is an essential cellular mechanism for bone adaptation to mechanical loading. The distraction regenerate has neovascularity, which appears to be more resistant to infection than is the case with bone grafting. During this period mineralization of callus occurs in osseous gap. With advances made in the past 40 years, the procedure is now being applied to deformities of the jaws and dentoalveolar process with a refined technique mastered by the lead author, Mikhail L.

Similar to osteogneesis development of the extraoral devices, recently developed intraoral devices have evolved from unidirectional to bidirectional to multidirectional distraction.

Unfavourable results with distraction in craniofacial skeleton

Samvhukov surgery from Tessier to distraction. Distraction osteogenesis of the craniofacial skeleton serves as an example of this most recent paradigm shift. Failure to recognise this leads to undue stress on the fixation pins culminating in either loosening of the pins at the site of bone anchorage or loosening of the pins at their site of distractor clamp anchorage.

Soft-tissue overstretching The forces of distraction in addition to helping in distraction of the bone ends may also at times lead to soft-tissue overstretching. Pseudoarthrosis may result as a result of these events during the late consolidation phase or remodelling phase. The distraction device should be secured using the distractjon pins and a test distraction should be performed intraoperatively to make sure that the fixation of the device ristraction the osteotomy is complete.

After distractor is fixed, osteotomy is completed and distractor is activated 2 mm. In order to correct mandibular deformities in three- dimensions, independent lengthening of mandibular corpus and ramus must be combined with gradual angular adjustments.


Later, Stader in used mandibular external fixator.

Unfavourable results with distraction in craniofacial skeleton

Conversely, rh-BMP-2 was effective in enhancing consolidation when applied as solid or liquid phase at day 0 and at the end of distraction. Distraction osteogenesis in maxillofacial surgery. Once healing is checked clinically and radiologically a repeat osteotomy is needed and the distraction can then be commenced.

Periodontal ligament Distraction Another interesting modification of the bone transport technique has been experimentally and clinically applied by Liou and Huang. The combination of position and simulated soft tissues affected distraction vector.

An anterior open bite has been created during the sagittal mandibular osteogenseis as a result of device placement almost parallel to the posterior cranjofacial of the mandible in lateral X-ray skull indicated by arrow. The use of plaster of Paris to fill large defects in bone.

Patient is viewed in natural head position, lips crabiofacial, seated condyle position and first tooth contact.

Craniofacial Distraction Osteogenesis – Mikhail L. Samchukov – Google Books

Fracture or splintering of the bone requiring DO is a relatively uncommon but a difficult complication to manage. Clin Orthop Relat Res. A variety of cephalometric analyses are available to map the precise location and extent of the deformity.

The tension-stress effect on the genesis and growth of tissues: Vasquez and Diner developed two types of intraoral bone-borne device for mandibular lengthening based on anatomic location of distraction, horizontal corpus or ascending ramus. An extensive library of case studies collected from world-renowned surgeons demonstrates the clinical application of the various techniques.

The advantages of rigid external distraction RED are that it is a fairly simple technique to apply intra-operatively, it is easy to activate for patients and can be removed craniifacial the need for a second operative procedure at the completion of consolidation.