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By these means, free fatty acids are made accessible as a fuel in other tissues. Please enter recipient e-mail address es. By agreement with the publisher, this book is accessible by the search feature, but cannot be browsed.

Support Center Support Center. Amino acids beeg activated for protein synthesis by a similar mechanism Section W H Freeman ; Allow this favorite library to be seen by others Keep this favorite library private. Thus, epinephrine, norepinephrine, glucagon, and adrenocorticotropic hormone induce lipolysis Figure How is the overall reaction driven forward?

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Reviews User-contributed reviews Add a review and share your thoughts with other readers. Hydrolysis by a phosphatase then gives glycerol. Hence, the stoichiometry of oxidation of palmitoyl CoA is. Some features of WorldCat will not be available.


Fatty acids are activated on the outer mitochondrial membrane, whereas they are oxidized in the mitochondrial matrix. WorldCat is the world’s largest library catalog, helping you find library materials online.


The answer is that pyrophosphate is rapidly hydrolyzed by a pyrophosphatase, and so the complete reaction is. Hence, glycerol can be converted into pyruvate or glucose in the liver, which contains the appropriate enzymes.

In this process, triacylglycerols are degraded to fatty acids and glycerol, which are released from the adipose tissue and transported to the energy-requiring tissues.

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These partial reactions are freely reversible. The lipase of adipose tissue are activated on treatment of these cells with the hormones epinephrine, norepinephrine, glucagon, and adrenocorticotropic hormone. Thus, glycerol and glycolytic intermediates are readily interconvertible.

The specific requirements or preferences of your reviewing publisher, classroom teacher, institution or organization should be biochmeia. Triacylglycerols Are Hydrolyzed by Cyclic AMP-Regulated Lipases The initial event in the utilization of fat as an energy source is the hydrolysis of triacylglycerols by lipases, an event referred to as lipolysis.

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However, formatting rules can vary widely between applications and fields of interest or study. The E-mail message field is required. The E-mail Address es you entered is are not in a valid format. W H Freeman; Finally, the translocase returns carnitine to the cytosolic side in exchange for an incoming acyl carnitine. Electrons from the FADH 2 prosthetic group of the reduced acyl CoA dehydrogenase are transferred to a second flavoprotein called electron-transferring flavoprotein ETF.


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Normally, the transfer of an acyl group from an alcohol to a sulfhydryl group is thermodynamically unfavorable. You may have already requested this item. First Three Rounds in the Degradation of Palmitate.

Don’t have an account? This reaction is catalyzed by carnitine acyltransferase I also called carnitine palmitoyl transferase Iwhich is bound to the outer mitochondrial membrane. National Center biochemiia Biotechnology InformationU.

The reverse process can take place by the reduction of dihydroxyacetone phosphate to glycerol 3-phosphate. Ubiquinone is thereby reduced to ubiquinol, which delivers its high-potential electrons to the second proton-pumping site of the respiratory chain Section Your list has reached the maximum number of items. Subsequent work demonstrated that they are activated before they enter the mitochondrial matrix.

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