ALCOHOL CONTENT DETERMINATION – authorSTREAM Presentation. density, if you have density of your initial product you can estmate and also build a curve using etanol to the mix and know the final density later. If you know the. Two methods are adopted for the estimation of this. In one Traditionally, determination of alcohol in galenicals is carried out by distillation method followed by.

Author: Voodoojin Malkree
Country: Syria
Language: English (Spanish)
Genre: History
Published (Last): 13 March 2014
Pages: 464
PDF File Size: 9.75 Mb
ePub File Size: 17.79 Mb
ISBN: 402-7-73054-973-1
Downloads: 80335
Price: Free* [*Free Regsitration Required]
Uploader: Faegami

Hercules Brochure VC E, pp. Collect distillate 2ml less than original volume of the test liquid 23mladjust the temperature at which the original test liquid was measuredadd water to make 25ml and mix.

USA – Alcohol-based antimicrobial compositions – Google Patents

WordPress Embed Customize Embed. Posted by The Pharmacist at These examples demonstrate evaporation retardation and the improved antibacterial activity of the instant invention.

The specific conditions used for the pig skin tests were as follows: Ratings of 0 to 10 were given to denote coverage; i. Allcohol plates were graded to indicate the extent of organism growth in the imprint. More preferably, the viscosifiers produce viscosities of about 50 to about cps in the final compositions.

From an antimicrobial standpoint, n-propyl alcohol is better than isopropyl alcohol, which in turn is better than ethyl alcohol. These examples are not intended to limit the scope galenicalw the invention. Antimicrobial film-forming composition, antimicrobial film, and method of verifying the presence of an antimicrobial film.


Wound dressing comprising silver sulfadiazine incorporated in animal tissue and method of preparation.


Two pieces of mounted skin were used for each sample tested. Here you can find all about Pharmacy Education, Industrial Pharmacy and relevant topics After dehairing, the hides were cut into smaller sections with a scalpel, rinsed in cold water, placed in plastic bags, sealed and frozen. Loss of alcohol by evaporation should be minimized. The two pieces of skin were then rubbed together for 15 seconds and allowed to air dry for 3 minutes to simulate normal evaporation before imprinting galenicxls skin samples onto the surface of a neutralizing growth media Standard Methods Agar galenicqls Lecithin and Polysorbate 80 from BBL.

This is a continuation of application Ser. Film-forming compositions of antihyperalgesic opiates and method of treating hyperalgesic conditions therewith.

From the chromatogram obtained, we can calculate the percentage of alcohol as by using the following formula: These alcohol compositions are very drying to the skin, evaporate quickly, and are easily spilled due to their watery nature. As examples of preferred compositions, the following may be listed. Compare the peak response ratio.

US5288486A – Alcohol-based antimicrobial compositions – Google Patents

Add twice the volume of distilled water. Add known concentration of internal standard acetone or acetonitrile unless otherwise specified in each. Chromatographic condition Carrier gas Helium or nitrogen Column packing Silica particles coated with polyethylene galfnicals Detector Flame Ionization Detector Column temperature Temperature of the column is maintained at o C Injection port temperature Temperature of the injection port o C.


The presentation is successfully added In Your Favorites. Year of fee payment: The distillate equal to the volume of original sample is collected. Preferred viscosifying agents are selected from the group consisting of hydroxypropyl cellulose estimatiom, polyvinyl pyrrlidones, and polymeric quaternary ammonium salts of hydroxyethyl cellulose reacted with a trimethyl ammonium substituted epoxide.

Determine peak response ratios. An inert gas such as gallium is used as carrier at a flow rate of about 60ml per minute. Treat the liquids that froth to a troublesome extent during distillation by ; 1- Rendering them strongly acidic with H 3 PO 4H 2 SO 4tannic acid 2- Treating with a slight excess of calcium chloride solution or with a small amount of paraffin or silicon oil before starting the distillation.

Alcohol-based skin disinfectants, because of their high vapor pressure, evaporate quickly. Add 10ml of internal standard Acetone for each 6ml of alcohol. Add 40ml of petroleum ether or petrol and shake for 2 minutes then take the lower layer.